Unveiling the Hidden Perils of Adenosine Toxicity

A Deep Dive into Cellular Chaos and Autoimmune Havoc

More stuff I never knew before. And I bet you weren’t aware of much of it, either. Because nobody is talking about adenosine toxicity.

Hopefully, you’ve heard of ATP, our universal energy currency.

The way that you use the energy in your food from fats, carbs and proteins (we’ll not mention alcohol) is to convert it into molecules of ATP.

So ATP is like energy coins your cells can use to pay the enzymes, transporters, and other molecules inside your body to do their work.

ATP is really cool.

When you don’t make enough, you become fatigued and unwell. The less ATP you make, the worse your health is.

Anyway, ATP is made out of different molecules joined together.

Unlocking the Secrets of Adenosine: A Vital Molecule Beyond ATP, Yet Concealing a Toxic Tale of Cellular Chaos

One of these molecules is called adenosine. ATP is actually adenosine triphosphate.

Adenosine is a key molecule. It’s not merely used to make ATP.

You need adenosine to activate vitamin B2 and vitamin B3 so that your body can use them.

Adenosine and a compound made from it (deoxy-adenosine) are necessary to synthesise your genetic material (DNA) and RNA (this is what you transcribe DNA into to make proteins).

So, adenosine is even more crucial to your health than ATP.

However, it turns out that adenosine and deoxyadenosine are toxic when they’re on their own and not bound with other molecules like DNA, RNA, vitamins B2 and B3, and ATP.

That’s right, adenosine and deoxyadenosine can start to cause cell damage.

This is why you either use adenosine and deoxyadenosine to make compounds like DNA, RNA, ATP, and activated vitamins B2 and B3 or break them down.

This means that the pool of free adenosine and deoxyadenosine inside and outside your cells is more of a tiny little puddle whenever you’re in good health.

Unraveling Adenosine Toxicity: When Mitochondrial Damage Unleashes a Flood of Harm

However, if your mitochondria or cells become damaged, you can release lots of adenosine.

This can happen due to poisoning by heavy metals like gadolinium or toxic compounds from moulds. Many commonly prescribed medications are also hazardous to your health. I’m not just talking about chemotherapy here.

It can also happen as a result of infection.

Malnutrition can also damage your mitochondria and cells and leave you vulnerable to toxicity damage.

Stress and sleep deprivation can also cause cellular dysfunction and lead to more vulnerability.

If cells die, you can even flood your tissues with adenosine and deoxyadenosine as they burst and release their contents. As a result, you can develop deoxyadenosine and adenosine toxicity.

This probably doesn’t happen much with programmed cell death (apoptosis) as, in this case, your cells actually tidy everything away and gradually shut up shop. So you’re left with not much more than an empty husk that’s already paid for its funeral service. Then your immune cells come along and gobble them up.

The Danger of Cell Death: The Toxic Free Radicals That Harm Surrounding Cells

But when cells suddenly die in unexpected and unpleasant ways, for example, due to a significant toxic exposure like a heavy metal (gadolinium, for instance), they don’t have time to wind down. They can burst and release all their contents into your tissues, including the adenosine and deoxyadenosine.

Although the adenosine and deoxyadenosine now treading water in the ocean between your cells are mostly still attached to other molecules as part of ATP, DNA, etc., you have many enzymes in your tissue fluid ocean, too.

So, it doesn’t take long for those enzymes to start chipping away and releasing adenosine and deoxyadenosine.

In addition, whenever mitochondria, released from your cell as it explodes like a dying star, get dumped into your tissue fluid, they can’t survive. And they also burst, unleashing a storm of free radicals and acid.

It’s like when Sigourney Weaver and pals shot up those alien xenomorphs in Alien, and the corrosive acid burnt through everything.

Downward Spiral: Escalating Harm as Free Radicals and Adenosine Run Riot in Your Cells

The free radicals and acids can attack the still-living cells around them. But they can also damage the DNA, RNA, ATP, etc.

Much of the calcium floating around was also released from the dead cell. Calcium should be controlled inside your cells with exquisite precision, not left to start a riot with free radicals and adenosine.

So now you’ve got an escalating problem with levels of harmful substances ballooning exponentially, including free radicals, acids, free calcium and free adenosine and deoxyadenosine.

The whole mix is pummelling your neighbouring cells and doing all sorts of damage. Your immune system gets called into action and starts trying to put out fires.

But since many cells are already past the point of saving by this stage, all your immune system can do is gobble up the destroyed cells and put the suffering ones out of their misery before they go rabid as well and burst, attacking their neighbouring cells in the process and setting off a chain reaction.

Part of this immune response involves producing antibodies to your own cells.

Antibodies that attack and destroy your own cells.

In other words, your immune system starts to produce autoantibodies.

It becomes an autoimmune disease.

With adenosine toxicity playing a key role.

Did you know...

…That when you’re exposed to toxins they can damage your metabolism enough to give you intolerances to many foods and chemicals? Find out more here.

And MRI dyes made from the toxic heavy metal gadolinium are one of the toxicants that can cause cellular, tissue and organ damage. Discover more about gadolinium toxicity here.

Catriona Walsh

Dr Catriona Walsh is a Nutrition and Lifestyle Coach, working in Belfast and Mid Ulster. She is a therapist near Antrim who can support your health goals. She provides advice on diet, supplements and lifestyle. She has improved her own health having experienced a decline following a gadolinium based contrast MRI.

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